Table 1. Effects of therapeutic oral administration of BBG9-1 on concentrations of acetic acid and L-lactic acid and pH in contents of the small intestine and large intestine.

		Non-RV	RV-Control	RV-BBG9-1
Small intestinal contents	Acetic acid (mg/mL)	178 ± 13	251 ± 7**	240 ± 11**
	L-lactic acid (mg/mL)	433 ± 34	651 ± 36*	512 ± 68
	pH	6.19 ± 0.03	6.40 ± 0.04**	6.43 ± 0.02**
Cecum and colonic contents	Acetic acid (mg/mL)	309 ± 57	317 ± 38	399 ± 31
	L-lactic acid (mg/mL)	344 ± 70	841 ± 55*	1262 ± 155**, #
	pH	5.75 ± 0.08	6.23 ± 0.15	5.79 ± 0.21

Oral administration of BBG9-1 and inoculation of RV were performed as described in the legend of Fig 2. Contents of the small intestine and contents of the cecum and colon were harvested 2 days after infection. Data are shown as means ± S.E. (n = 6 pups for each group).

*p < 0.05.

**p < 0.01 compared with the Non-RV group.

^#p<0.05 with the RV-Control group by the Tukey-Kramer test or Steel Dwass test.