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. 2017 Mar 27;12(3):e0174550. doi: 10.1371/journal.pone.0174550

Fig 3. Blockade of gp120 CD4-binding site inhibits IL-10 production by monocytes.

Fig 3

A) Representative experiment and B) flow cytometry analysis of IL-10 expression on PBMC CD3- CD14+ cells detected by intracellular staining after gp120 stimulation in absence or presence of sCD4 or the CD4-binding site VRC01 antibody at a molar ratio of 1:1 with gp120. Statistical analysis were performed with t-tests to compare to the mock control (** p<0.01).