Table 1.
Expression of IRAK1 in different types of liver tissues
| Tissue | Patients (n) | IRAK1 negative, n (%) | IRAK1 positive, n (%) | χ2 | P-value |
|---|---|---|---|---|---|
| HCC vs | 171 | 88 (51.5) | 83 (48.5) | ||
| Para-carcinoma tissue | 171 | 112 (65.5) | 59 (34.5) | 6.936 | 0.008 |
| Liver cirrhosis | 37 | 28 (75.7) | 9 (24.3) | 7.230 | 0.007 |
| Normal | 33 | 28 (84.8) | 5 (15.2) | 12.570 | ,0.001 |
| Para-carcinoma tissue vs | 171 | 112 (65.5) | 59 (34.5) | ||
| Liver cirrhosis | 37 | 28 (75.7) | 9 (24.3) | 1.432 | 0.231 |
| Normal | 33 | 28 (84.8) | 5 (15.2) | 4.811 | 0.028 |
| Liver cirrhosis vs | 37 | 28 (75.7) | 9 (24.3) | ||
| Normal | 33 | 28 (84.8) | 5 (15.2) | 0.917 | 0.338 |
Note: Linear by linear association test (χ2=18.871, P<0.001) among normal, liver cirrhosis and para-carcinoma tissues, and HCC revealed an increasing trend of IRAK1 expression in these four tissues.
Abbreviation: HCC, hepatocellular carcinoma.