Table 3.
No Differences at Endpoint in Attention and Memory Outcomes Between Randomized Groups, N = 150
| Basic M (SE) | Augmented M (SE) | F (1,146) | p | Cohen's d (95% CI) | |
|---|---|---|---|---|---|
| Omissionsa | 4.75 (0.19) | 4.57 (0.40) | 0.14 | 0.71 | 0.07 (−0.25, 0.39) |
| Comissions | 24.09 (0.83) | 25.34 (1.21) | 0.69 | 0.41 | −0.14 (−0.46, 0.18) |
| Reaction time (ms) | 464.57 (10.67) | 455.52 (14.35) | 0.52 | 0.47 | 0.08 (−0.24, 0.40) |
| Reaction time SEa (ms) | 3.98 (0.10) | 3.90 (0.17) | 0.14 | 0.71 | 0.07 (−0.25, 0.39) |
| Digit span (standard score) | 10.37 (0.28) | 10.03 (0.60) | 0.24 | 0.62 | 0.09 (−0.23, 0.41) |
| Digits forward (raw score) | 8.21 (0.20) | 8.30 (0.35) | 0.05 | 0.83 | −0.04 (−0.36, 0.28) |
| Digits backward (raw score) | 3.96 (0.16) | 4.05 (0.31) | 0.06 | 0.80 | −0.04 (−0.36, 0.28) |
Basic = stimulant+parent training+placebo. Augmented = stimulant+parent training+risperidone. Sample size reflects subjects with at least one data point in the analysis. Estimated marginal means with standard error were calculated from the mixed model, controlling for site and mean-centered mg/kg dose of risperidone. In the double-blind analyses, the groups (Augmented and Basic) were constrained to equality at week 3. The effect of time in the week 3 to 9 analyses was nonsignificant for all outcomes.
a
Square-root transformed.