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. 2017 Mar 1;23(3):146–155. doi: 10.1089/ten.tec.2016.0492

FIG. 6.

FIG. 6.

Sprayed platelet fibrin patch attenuates LV remodeling and preserves cardiac function. (A) Representative Masson's trichrome-stained heart sections obtained from hearts 21 days after surgery. Scar tissue and viable myocardium are identified by blue and red stains respectively; (B–E) Quantitative analysis of infarct size, LV cavity area, infarct wall thickness, and viable tissue percentages from the Masson's trichrome images (n = 3 animals per group); (F, G) Left ventricular fraction shortening (LVFS) and left ventricular ejection fraction (LVEF) were measured by echocardiography at baseline (4 h post-MI) and 21 days afterward in SHAM, MI alone, MI + Fibrin Spray, and MI + Platelet Fibrin Spray groups (n = 6 animals per group); *p < 0.05 when compared with the SHAM group; #p < 0.05 when compared with MI + Platelet Fibrin Spray group; &p < 0.05 when compared with MI Alone group; %p < 0.05 when compared with MI + Fibrin Spray group. LV, left ventricular.