FIG. 7.

Sprayed platelet fibrin patch promotes endogenous repair and attenuates tissue apoptosis. (A) Cardiomyocytes stained with alpha sarcomeric actin (α-SA) (red) in the hearts 21 days after MI surgery. The numbers of α-SA positive cardiomyocytes were quantified (n = 3 animals per group). (B) Endothelial cells stained with von Willebrand factor (vWF) (red) in the hearts 21 days after MI surgery. The numbers of vWF-positive endothelial cells were quantified (n = 3 animals per group). (C) Representative fluorescent micrographs showing the presence of TUNEL⁺ apoptotic cells (red) in the hearts of MI alone and MI + Platelet Fibrin Spray groups. The numbers of apoptotic-positive cells were quantified (n = 3 animals per group). Scale bars = 100 μm. *p < 0.05 when compared with the treated with “MI Alone.”