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. 2017 Mar 1;27(2):125–131. doi: 10.1089/cap.2016.0107

Table 2.

Pairwise Contrasts of Mean Scores Across All Parent Target Problem Panel Ratings and Parent-Rated Aberrant Behavior Checklist Hyperactivity Subscale After 1 Week on Each Active Dose Versus 1 Week on Placebo in the 4-Week Crossover Trial

  PTP ratinga ABC hyperactivity p Effect sizeb
Dose Mean (SE) Mean (SE)c PTP ABC PTP ABC
Placebo (n = 59) 4.37 (0.13) 25.97 (1.43)        
Low (n = 60) 4.29 (0.14) 23.35 (1.51) 0.63 0.14 0.09 0.26
Medium (n = 56)d 4.12 (0.13) 21.22 (1.41) 0.11 <0.01 0.27 0.46
High (n = 43)e 3.99 (0.16) 21.44 (1.49) 0.04 0.01 0.40 0.44
a

Means are averaged over two PTPs, unless a subject had only one PTP.

b

Effect sizes calculated by subtracting model-based means and dividing by pooled SD for placebo; Placebo pooled SD for PTP = 0.94; Placebo pooled SD for ABC = 10.27.

c

ABC Hyperactivity subscale scores are not exactly as reported in RUPP Autism Network (2005) because of slight differences in sample size.

d

Medium dose scores for subjects randomized to receive medium dose twice were averaged.

e

Change in sample size because of missing data and modifications in random assignment to dose (see text).

ABC, Aberrant Behavior Checklist; PTPs, parent target problems; SE, standard error.