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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Neurogastroenterol Motil. 2016 Oct 25;29(4):10.1111/nmo.12984. doi: 10.1111/nmo.12984

Figure 1. Bone marrow-derived macrophages can be activated to a classically-activated M1 or alternatively-activated M2 macrophage phenotype by external stimuli.

Figure 1

Expression of iNOS and IL-6 RNA, markers of classically-activated M1 macrophages and Arg1, FIZZ, IL-4, IL-5, and IL-10 RNA, markers of alternatively-activated M2 macrophages in bone marrow-derived macrophages following treatment with IFNγ or IL-10/TGFβ. Data were normalized to expression in unstimulated control macrophages (Unst). Beta-actin was used as a housekeeping control. Data are the means ± SEM of n = 5 independent experiments, * indicates P < 0.05 vs unstimulated cells, one-sample t-test.