Table 3.
Logistic Regression Analyses of Baseline Predictors on Severe Early Satiety* in Idiopathic and Diabetic Gastroparetics (n=196)
| Baseline characteristic | Unadjusted Analyses
|
Adjusted Analysis
|
||||
|---|---|---|---|---|---|---|
| OR | CI | P† | OR | CI | P‡ | |
| Etiology (diabetic vs idiopathic) | 0.83 | (0.46, 1.51) | 0.54 | 0.47 | (0.19, 1.18) | 0.11 |
| Gender (female vs male) | 0.92 | (0.42, 2.03) | 0.84 | 0.29 | (0.10, 0.88) | 0.03 |
| BMI (kg/m2) | 0.95 | (0.91, 0.99) | 0.01 | 0.91 | (0.86, 0.96) | 0.001 |
| PAGI-SYM, nausea score | 1.63 | (1.32, 2.00) | <0.001 | 1.24 | (0.93, 1.67) | 0.14 |
| PAGI-SYM, vomiting score | 1.36 | (1.14, 1.63) | 0.001 | 1.28 | (0.98, 1.68) | 0.07 |
| PAGI-SYM, bloating score | 1.75 | (1.42, 2.16) | <0.001 | 1.98 | (1.48, 2.64) | <0.001 |
| PAGI-SYM, upper abdominal pain sub-score | 1.83 | (1.46, 2.29) | <0.001 | 1.55 | (1.17, 2.07) | 0.002 |
| PAGI-SYM, GERD sub-score | 1.19 | (0.97, 1.46) | 0.10 | 0.77 | (0.57, 1.03) | 0.08 |
| SF-36, mental score | 1.00 | (0.98, 1.02) | 0.96 | 1.03 | (1.01, 1.05) | 0.02 |
| Solid gastric scintigraphy, percent retention at 4 hours | 1.02 | (1.00, 1.03) | 0.02 | 1.03 | (1.00, 1.05) | 0.007 |
Severe early satiety defined as ‘severe’ or ‘very severe’ inability to finish a normal-sized meal score on the PAGI-SYM instrument
Unadjusted odds ratios, 95% confidence limits, P values determined from logistic regression models of severe early satiety on each predictor
Adjusted odds ratios, 95% confidence limits, P values were determined from a multiple logistic regression analyses of severe early satiety using all baseline predictors indicated. This model was determined from Akaike Information criteria (AIC) best subsets variable selection using a candidate set of baseline variables: gender, age at enrollment, etiology, race, BMI, SF-36 physical score, SF-36 mental score, PAGI-QOL total score, solid GES 2 hour retention percent, solid GES 4 hour retention percent, and the following PAGI-SYM items: nausea score, vomiting score, retching score, bloating score, stomach visibly larger score, upper abdominal pain sub-score, and GERD sub-score.