Table 1.

Summary of biomarker measures.

Marker	COU-AA-301 study (N = 644)		ELM-PC4 study (N = 908)
	Median	(Range)	Median	(Range)
Baseline albumin	4.1	(2.9–4.9)	4.4	(2.5–5.4)
Baseline ALK	114.5	(33–4617)	96.0	(35–3,281)
Baseline CTC	4.0	(0–100)	2.0	(0–5,153)
Baseline hemoglobin	12.0	(7.3–16.5)	12.9	(4.7–17.5)
Baseline LDH	215.0	(84–3,373)	186.0	(67–1,868)
Baseline PSA	119.2	(0.4–10,110)	49.7	(1.7–3,906)
Week 13 CTC	1.0	(0–100)	0	(0–1,635)
Week 13 PSA	97.5	(0.1–8,582)	31.6	(0–7682)
Age	70	(42–95)	71	(49–89)

Abbreviations: ALK, alkaline phosphatase; CTC, circulating tumor cells; LDH, lactate dehydrogenase; PSA, prostate-specific antigen.