Table 3. Cox Model for RAS with Time-Dependent Covariates.
| Univariable | Multivariable † | |||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
|
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|
|
|
|
|
|
| DAD < 6 months | 1.8 | 0.92 - 3.7 | 0.0867 | |||
| DAD ≥ 6 months | 16.0 | 6.8 - 37.5 | 0.0001 | 6.2 | 2.0 - 18.8 | 0.0014 |
| OP < 6 months | 1.3 | 0.7 - 2.6 | 0.4088 | |||
| OP ≥ 6 months | 6.6 | 3.2 - 13.4 | 0.0001 | 3.2 | 1.1 - 8.8 | 0.0275 |
| LB < 6 months | 1.5 | 0.8 - 2.6 | 0.2057 | |||
| LB ≥ 6 months | 2.0 | 1.1 - 3.7 | 0.0336 | 1.0 | 0.5 - 2.2 | 0.9992 |
| AR < 6 months | 1.8 | 1.0 - 3.1 | 0.0397 | 1.8 | 1.0 - 3.2 | 0.0395 |
| AR ≥ 6 months | 2.0 | 1.1 - 3.6 | 0.0262 | 1.6 | 0.8 - 3.3 | 0.1774 |
Definition of abbreviations: CLAD = chronic lung allograft dysfunction; HR = hazards ratio; CI = confidience interval; ALI = acute lung injury; OP = organizing pneumonia; LB = lymphocytic bronchiolitis; AR = acute rejection;
†
Multivariable model includes only the variables listed.