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. 2017 Feb 11;26(4):650–661. doi: 10.1002/pro.3122

Table 1.

Effective Dosages and CAS Numbers of Small‐Molecule Inhibitors Discussed in This Paper Grouped by Their Targets

Target Compounds Effective dosage CAS No. References
Dvl protein NSC668036 237 µM 144678‐63‐7 19
3289‐8625 10.6 µM 294891‐81‐9 20
J01‐017a 1.5 ± 0.5 μM 22
TMEM88 2 ± 0.2 µM 24
KY‐02061 0.4–12 µM 25
KY‐02327 0.13–4 µM 25
BMD4702 38 µM 335206‐54‐7 26
Niclosamide 24 µM 50‐65‐7 28
DK‐520 8.308 ± 0.8 µM 29
Sulindac 0.186 µM 38194‐50‐2 31
β‐catenin destruction complex Pyrvinium <10 nM 7187‐62‐4 37
Natural compounds Derricin 10 µM 34211‐25‐1 40
Derricidin 50 µM 38965‐74‐1 40
Carnosic acid 5‐20 µM 3650‐09‐7 41
TCF/LEF transcription reporter ICG‐001 3 µM 847591‐62‐2 43
PNU‐74654 100 µM 113906‐27‐7 45
Windorphen 4.2 µM 19881‐70‐0 47
Prcn IWP‐L6 10 nM 1427782‐89‐5 48
Wnt‐C59 >60 µM 1243243‐89‐1 49
LGK974 0.3–1 nM 1243244‐14‐5 51
ETC‐159 2.9 nM 1638250‐96‐0 52
TNKS XAV939 0.099 µM 284028‐89‐3 55
E7449 50‐120 nM 1140964‐99‐3 57