Table 1.
Target | Compounds | Effective dosage | CAS No. | References |
---|---|---|---|---|
Dvl protein | NSC668036 | 237 µM | 144678‐63‐7 | 19 |
3289‐8625 | 10.6 µM | 294891‐81‐9 | 20 | |
J01‐017a | 1.5 ± 0.5 μM | 22 | ||
TMEM88 | 2 ± 0.2 µM | 24 | ||
KY‐02061 | 0.4–12 µM | 25 | ||
KY‐02327 | 0.13–4 µM | 25 | ||
BMD4702 | 38 µM | 335206‐54‐7 | 26 | |
Niclosamide | 24 µM | 50‐65‐7 | 28 | |
DK‐520 | 8.308 ± 0.8 µM | 29 | ||
Sulindac | 0.186 µM | 38194‐50‐2 | 31 | |
β‐catenin destruction complex | Pyrvinium | <10 nM | 7187‐62‐4 | 37 |
Natural compounds | Derricin | 10 µM | 34211‐25‐1 | 40 |
Derricidin | 50 µM | 38965‐74‐1 | 40 | |
Carnosic acid | 5‐20 µM | 3650‐09‐7 | 41 | |
TCF/LEF transcription reporter | ICG‐001 | 3 µM | 847591‐62‐2 | 43 |
PNU‐74654 | 100 µM | 113906‐27‐7 | 45 | |
Windorphen | 4.2 µM | 19881‐70‐0 | 47 | |
Prcn | IWP‐L6 | 10 nM | 1427782‐89‐5 | 48 |
Wnt‐C59 | >60 µM | 1243243‐89‐1 | 49 | |
LGK974 | 0.3–1 nM | 1243244‐14‐5 | 51 | |
ETC‐159 | 2.9 nM | 1638250‐96‐0 | 52 | |
TNKS | XAV939 | 0.099 µM | 284028‐89‐3 | 55 |
E7449 | 50‐120 nM | 1140964‐99‐3 | 57 |