Table 2.
Odds Ratios for Mortality with increasing BNP Levels within Subgroups by BMI Category and Heart Failure Type
| BMI Category | HFrEF | HFpEF | ||
|---|---|---|---|---|
| 1-Yr mortality (%) | OR (95% CI) | 1-Yr mortality (%) | OR (95% CI) | |
| Underweight | 50.8 | 2.99 (0.44–20.42) | 48.3 | 4.12 (0.44–38.62) |
| Normal Weight | 37.0 | 1.43 (0.71–2.89) | 40.9 | 1.35 (0.62–2.95) |
| Overweight | 28.7 | 1.74 (0.77–3.89) | 30.4 | 1.51 (0.49–4.60) |
| Obese | 27.2 | 1.32 (0.54–3.22) | 18.0 | 2.16 (0.76–6.13) |
| Morbidly Obese | 20.4 | 11.21 (2.64–47.58) | 23.7 | 0.91 (0.34–2.38) |
P-value for interaction between BMI, LVEF categories and log BNP = 0.094
The adjusted Odd’s Ratios (ORs) and 95% Confidence Intervals (CI) are for mortality per unit increase in log10 BNP.
The models are adjusted for age, gender, race, systolic blood pressure at admission, highest BUN, prior history of heart failure hospitalization, beta-blockers at discharge, statins at discharge, ACE inhibitors or angiotensin II receptor blockers at discharge, intravenous diuretics during hospitalization, history of pulmonary hypertension, pulmonary embolism, connective tissue disease, stroke/TIA and the interactions terms for BMI, LVEF type and log BNP. The overall OR and 95% CI was 1.62 (1.17 – 2.24). The overall one-year mortality was 30.9%.