Table 3. Prevalence of Hypothyroidism and Hyperthyroidism in Korea according to Age and TPOAb Positivity.
Variable | Overt hypothyroidisma | Subclinical hypothyroidismb | Overt hyperthyroidismc | Subclinical hyperthyroidismd | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Total | Male | Female | Total | Male | Female | Total | Male | Female | Total | Male | Female | |
Total population, stratified by age, yr | ||||||||||||
All ages | 0.73 | 0.40 | 1.10 | 3.10 | 2.26 | 4.04 | 0.54 | 0.30 | 0.81 | 2.98 | 2.43 | 3.59 |
10–18 | 0.00 | 0.00 | 0.00 | 3.60 | 2.40 | 5.23 | 0.94 | 0.63 | 1.34 | 1.60 | 1.41 | 1.85 |
19–29 | 0.20 | 0.00 | 0.45 | 2.34 | 2.20 | 2.52 | 0.25 | 0.19 | 0.31 | 2.26 | 1.18 | 3.65 |
30–39 | 0.24 | 0.00 | 0.54 | 2.15 | 1.71 | 2.68 | 0.64 | 0.20 | 1.17 | 2.73 | 1.86 | 3.78 |
40–49 | 0.98 | 0.23 | 1.91 | 2.86 | 2.09 | 3.81 | 0.49 | 0.22 | 0.83 | 2.88 | 3.05 | 2.66 |
50–59 | 1.44 | 0.97 | 1.93 | 5.09 | 2.98 | 7.32 | 0.78 | 0.00 | 1.60 | 3.57 | 3.60 | 3.53 |
60–69 | 1.22 | 1.21 | 1.22 | 2.62 | 2.17 | 2.98 | 0.26 | 0.60 | 0.00 | 4.30 | 3.14 | 5.20 |
≥70 | 0.58 | 1.13 | 0.00 | 2.97 | 2.41 | 3.55 | 0.83 | 1.63 | 0.00 | 3.13 | 3.75 | 2.48 |
Total population, stratified by TPOAb | ||||||||||||
Positive TPOAb | 5.16 | 5.92 | 4.81 | 10.88 | 9.10 | 11.69 | 2.92 | 2.44 | 3.13 | 3.80 | 4.06 | 3.67 |
Negative TPOAb | 0.39 | 0.16 | 0.66 | 2.49 | 1.95 | 3.13 | 0.35 | 0.20 | 0.54 | 2.92 | 2.36 | 3.58 |
Values are expressed as percentage. TPOAb positivity was defined as >34.0 IU/mL.
TPOAb, anti-thyroid peroxidase antibody.
aOvert hypothyroidism was defined thyroid stimulating hormone (TSH) (mlU/L) >97.5th percentile and free thyroxine (fT4) (ng/dL) <0.9; bSubclinical hypothyroidism was defined TSH (mlU/L) >97.5th percentile and 0.9≤fT4 (ng/dL)<1.8; cOvert hyperthyroidism was defined TSH (mlU/L) <2.5th percentile and fT4 (ng/dL) ≥1.8; dOvert hyperthyroidism was defined TSH (mlU/L) <2.5th percentile and 0.9≤fT4 (ng/dL)<1.8.