Fig. 5.

No changes in the intrinsic properties of cortical neurons upon partial or total elimination of Kiaa0319. a–c Superimposed responses of pyramidal cells to suprathreshold depolarising and hyperpolarising current injection for electroporated cells in wild-type (a; +/+), heterozygous (b; F/+) and homozygous (c; F/F) floxed animals. d–f Action potential phase (dV/dT) plots for 10 action potentials shown in panels a–c. g–o Active (g–l) and passive membrane properties (m–o) for electroporated cells recorded from +/+ (n = 6), F/+ (n = 5) and F/F (n = 5) animals. No significant differences were observed. The data represent mean ± SEM. Significance was assessed by Kruskal–Wallis test with Dunn’s correction for multiple comparisons