Figure 5.

SOCS3 is a direct target of miR-384. (A) Illustration of the sequence match between miR-384 and SOCS3 mRNA determined using TargetScan. (B) Luciferase activity of reporter vectors containing wild-type (WT) or mutated (MUT) SOCS3 3′-UTR co-transfected with miR-384 or control miR (ctrl; n = 3 per group). (C) MFI analyses of flow cytometry for SOCS3 in GFP⁺ naïve T cells 3 days post-transfection (n = 3 per group). Data are presented as means ± SD. *p < 0.05 and **p < 0.01. Data shown are single representative results from three independent experiments.