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. 2017 Mar 28;8:510. doi: 10.3389/fmicb.2017.00510

Table 4.

Summary of phenotypes of S. Typhimurium isolates showing concurrently decreased susceptibility to ciprofloxacin and cephalosporins and their corresponding resistance genes.

Strain MIC (μg/mL)
 QRDR mutation
 PMQR ESBL mphA
FOX CRO XNL CIP AZI gyrA parC
SHI 1G663 >32 4 8 4 4 WT WT qnrB/aac(6′)-Ib-cr
SHI 1G664 >32 8 >8 4 2 WT WT qnrB/aac(6′)-Ib-cr blaOXA
SHI 1G665 >32 32 8 4 4 WT WT qnrB/aac(6′)-Ib-cr blaOXA
SH11G680 4 >64 >8 >4 2 S83F/D87N S80R blaOXA/blaCTX-M-55
SHI 1G993 >32 16 >8 >4 256 S83F/D87N S80R blaOXA mphA
SH11G1304 2 >64 >8 2 4 D87Y WT aac(6′)-Ib-cr blaOXA/blaCTX-M-27
SH11G1306 2 >64 >8 2 4 D87Y WT
SHI 2G734 32 <0.25 2 2 4 D87Y WT aac(6′)-Ib-cr blaTEM
SHI 2G889 32 <0.25 2 4 8 D87Y WT aac(6′)-Ib-cr blaOXA/blaCTX-M-14/blaTEM
SH12G978 32 >64 >8 2 64 WT WT qnrB/aac(6′)-Ib-cr blaCTX-M-15/blaTEM
SHI 2G1005 8 >64 >8 >4 64 S83F/D87N T57S/S80R aac(6′)-Ib-cr blaCTX-M-65/blaTEM
SHI 3G355 2 >64 >8 2 4 D87N WT aac(6′)-Ib-cr blaTEM
SHI 3G769 2 >64 >8 2 4 D87N WT aac(6′)-Ib-cr blaCTX-M-14
SHI 3G938 16 >64 >8 2 4 D87N WT blaOXA/blaCTX-M-55
SHI 3G939 16 >64 >8 2 4 D87N WT blaOXA/blaCTX-M-55
SH13G1219 8 >64 >8 >4 128 D87Y WT aac(6′)-Ib-cr blaCTX-M-15/blaTEM mphA
SHI 3G1825 2 >64 >8 >4 128 D87Y WT aac(6′)-Ib-cr blaCTX-M-15/blaTEM mphA
SHI 4G287 4 >64 >8 2 8 WT WT aac(6′)-Ib-cr blaOXA/blaCTX-M-125
SHI 4G294 8 64 >8 2 8 D87N WT aac(6′)-Ib-cr blaOXA/blaCTX-M-125
SHI 4G300 4 64 >8 2 64 D87N WT aac(6′)-Ib-cr blaOXA/blaCTX-M-125
SHI 4G1345 4 >64 >8 2 4 D87Y WT blaOXA/blaCTX-M-55/blaTEM
SH14G1601 2 >64 >8 2 4 D87N WT aac(6′)-Ib-cr blaCTX-M-55

FOX, cefoxitin; CRO, ceftriaxone; XNL, ceftiofur; CIP, ciprofloxacin; AZI, azithromycin; WT, wild type.