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. 2017 Mar 28;7:98. doi: 10.3389/fcimb.2017.00098

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Copyright © 2017 Dong, Yang, Wang, Wei, Wang, Hao, Shen, Huang, Zhang and Lian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Induction of phosphorylated STAT-1 in response to IL-15 stimulation in the presence of anti-common γc receptor neutralizing antibody. PBMCs were selected from 10 of CHB patients which were enrolled in Figure 1. (A) Representative histogram of pSTAT-1 were shown. The light gray represented isotype control. The purple dashed line represented untreated PBMCs. The blue dashed line represented IL-15 stimulated normal PBMCs. The red line represented γc receptor neutralizing antibody treated PBMCs. The green line represented IL-15 stimulated, γc receptor neutralizing antibody treated PBMCs. (B) Comparison of mean fluorescence intensity (MFI) value of pSTAT-1 among groups. The dashed line represented background levels from isotype control. Data were presented as mean and standard deviation. Mann-Whitney test was used for comparison between groups.