| Serotonin system |
PR and SPR monkeys showed decreased CSF levels of 5-HIAA |
Fahlke et al., 2000; Higley et al., 1996a; Maestripieri et al., 2006; Shannon et al., 2005
|
|
|
PR monkeys showed decreased SERT binding potential |
Ichise et al., 2006 |
|
|
VFD monkeys were hyporesponsive to the serotonergic probe mCPP |
Rosenblum et al., 1994 |
|
| Catecholamine system |
PR monkeys showed lower CSF concentrations of HVA and attenuated NE secretion |
Clarke et al., 1999; Clarke et al., 1996
|
|
|
VFD monkeys were hyper responsive to the noredrenergic probe yohimbine |
Rosenblum et al., 1994 |
|
|
PR monkeys showed significantly lower DOPAC concentrations |
Clarke et al., 1999; Clarke et al., 1996
|
|
| HPA axis dysregulation |
Hypercortisolism |
Hormone level |
Barrett et al., 2009; Coplan et al., 2005; Coplan et al., 1996; Coplan et al., 2001; Suomi, 1991
|
Essex et al., 2002; Flinn & England, 1997; Gunnar et al., 2001; Kaufman et al., 1997
|
|
|
Increased HPA response |
Fahlke et al., 2000; Higley et al., 1992; Kraemer et al., 1983, 1984; Sánchez et al., 2005; Suomi, 1991
|
Heim et al., 2000b; Kikusui & Mori, 2009; Pesonen et al., 2010
|
|
Hypocortisolism |
Hormone level |
Clarke et al., 1998; Capitanio et al., 2005; Shannon et al., 1998
|
Brand et al., 2010; De Bellis et al., 1994; Heim et al., 2000a
|
|
|
Decreased HPA response |
Barr et al., 2004; Capitanio et al., 2005; Clarke, 1993; Dettling et al., 1998; Dettling et al., 2002a, b ; Lyons et al., 2000; Parker et al., 2004
|
Carpenter et al., 2009; Elzinga et al., 2008; Hart et al., 1995
|
