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. 2017 Apr;17(4):411–421. doi: 10.1016/S1473-3099(16)30514-X

Figure 3.

Figure 3

Oxfordshire Clostridium difficile IRR by fluoroquinolone resistance and genotype

For genotypes with more than 10% resistant isolates (denoted FQR), rates were calculated separately for C difficile infections caused by fluoroquinolone-susceptible and resistant isolates. To show that the difference in IRR for resistant and susceptible isolates is not driven solely by the decline in ST1(027), rates were also calculated for all non-ST1(027) genotypes together, as well as for all genotypes with more than 10% resistant isolates (excluding ST1(027)) and for all genotypes with 10% or less resistant isolates (FQS). Heterogeneity between IRRs in C difficile infections caused by fluoroquinolone-resistant versus fluoroquinolone-susceptible isolates: all p<0·0001, non-ST1 p<0·0001, non-ST1 FQR p<0·0001, ST42 p<0·0001, ST37 p=0·00015, ST3 p=0·00070, ST35 p=0·92, ST11 p=0·0053. The dotted vertical lines separate out the different ways the isolates were divided for the different analyses. The horizontal dotted line represents an IRR of 1. IRR=annual incidence rate ratio.