Table 1.
Control (n=89) | Pentoxifylline (n=89) | P | |
---|---|---|---|
Age, years¥ | 59.0 (53.0 to 69.0) | 59.0 (53.0 to 69.0) | 0.62 |
Male† | 74 (83.0) | 72 (80.9) | 0.69 |
Previous CVA† | 7 (7.9) | 4 (4.5) | 0.35 |
Previous RF† | 2 (2.2) | 3 (3.4) | 0.65 |
Previous COPD† | 4 (4.5) | 7 (7.9) | 0.35 |
Previous PVD† | 1 (1.1) | 1 (1.1) | 0.99 |
Trop-T, ng/mL¥ | 20.9 (7.9 to 75.0) | 15.4 (7.7 to 79.6) | 0.56 |
TNF-a, pg/mL¥ | 139 (30.9 to 1117.5) | 472 (115.6 to 1701) | 0.02 |
IL-6, pg/mL¥ | 133.4 (38.2 to 246.0) | 195.0 (92.0 to 256.0) | 0.01 |
EF, %¥ | 30.0 (25.0 to 30.0) | 30.0 (25.0 to 30.0) | 0.91 |
WBC, x103/cmm¥ | 7.6 (6.2 to 9.3) | 7.6 (6.5 to 9.1) | 0.85 |
Hgb, mg/dL¥ | 13.3 (12.3 to 14.4) | 13.7 (12.6 to 14.9) | 0.06 |
Hct, %¥ | 40.8 (37.9 to 43.1) | 41.5 (38.45 to 44.7) | 0.10 |
Plt, x103/cmm¥ | 208.0 (171.5 to 246.5) | 207.0 (168.5 to 257.0) | 0.77 |
BUN, mg/dL¥ | 38.0 (31.0 to 46.7) | 38.0 (30.0 to 43.3) | 0.49 |
Cr, mg/dL¥ | 1.0 (0.90 to 1.25) | 1 (0.8 to 1.2) | 0.12 |
Values represent median (interquartile range):
Number (%):
BUN - blood urea nitrogen; cmm - cubic millimeter; COPD - chronic obstructive pulmonary disease; Cr - creatinine; CVA - cerebrovascular accident; EF - ejection fraction; Hct - hematocrit; Hgb - hemoglobin; IL - interleukin; mg/dL - milligram/deciliter; ng/dL - nanogram/deciliter; pg/dL - picogram/deciliter; Plt - platelet; Pre-Op - pre-operative; PVD - peripheral vascular disease; RF - renal failure; TNF - tumor necrosis factor; Trop-T - troponin-T; WBC - white blood cell