Table 2.
A comparison of post-op values between the two groups and the comparison of changes between them
| Control | Pentoxifylline | Post-op | Change | |||||
|---|---|---|---|---|---|---|---|---|
| Pre-op | Post-op | Change | Pre-op | Post-op | Change | P | P | |
| Trop-T, ng/mL | 20.9 (7.9 to 75.0) | 304.6 (197.5 to 449.5) | 255.2 (150.1 to 379.0) | 15.4 (7.7 to 79.6) | 308.2 (200.7 to 447.2) | 242.4 (137.8 to 406.7) | 0.94 | 0.68 |
| TNF-a, pg/mL | 139.0 (30.9 to 1117.5) | 40.0 (3.6 to 135.0) | -83.1 (-977.5 to 0.4) | 472.0 (115.6 to 1701.0) | 18.0 (1.7 to 73.0) | -427.8 (-1518.3 to -57.8) | 0.01 | 0.01 |
| IL-6, pg/mL | 133.4 (38.2 to 246.0) | 40.00 (25.5. to 98.6) | -55.0 (-152.3 to 6.8) | 195.0 (92.0 to 256.0) | 32.0 (18.3 - 54.5) | -135.6 (-226.5 to -30.0) | 0.08 | 0.01 |
| EF , % | 30.0 (25.0 to 30.0) | 30.0 (25.0 to 35.0) | 0.0 (0.0 to 5.0) | 30.0 (25.0 to 30.0) | 30.0 (27.5 to 35.0) | 5.0 (0.0 to 5.0) | 0.06 | 0.01 |
| WBC, x103/cm | 7.6 (6.2 to 9.3) | 13.4 (99.0 to 18.4) | 5.4 (2.0 to 9.5) | 7.6 (6.5 to 9.1) | 12.3 (10.4 to 15.1) | 4.9 (2.8 to 7.5) | 0.44 | 0.66 |
| Hgb, mg/dL | 13.3 (12.3 to 14.4) | 9.6 (8.8 to 10.5) | -3.6 (-4.6 to -2.6) | 13.7 (12.6 to 14.9) | 10.0 (9.4 to 10.6) | -3.7 (-4.8 to -2.8) | 0.03 | 0.77 |
| Hct, % | 40.8 (37.9 to 43.1) | 29.3 (27.6 to 32.0) | -10.8 (-13.4 to -7.5) | 41.5 (38.4 to 44.7) | 30.6 (29.1 to 32.0) | -11.0 (-13.2 to -8.1) | 0.02 | 0.93 |
| Plt, x103/cm | 208.0 (171.5 to 246.5) | 152.0 (125.2.0 to 191.5.0) | -47.0 (-80.0 to -28.1) | 207.0 (168.5 to 257.0) | 146.2 (115.8 to 182.7) | -55.8 (-84.7 to -33.0) | 0.29 | 0.25 |
| BUN, mg/dL | 38.0 (31.0 to 46.7) | 32.9 (26.2 to 41.0) | -4.2 (-11.5 to 1.9) | 38.0 (30.0 to 34.3) | 33.0 (25.5 to 38.0) | -3.0 (-12.6 to -1.5) | 0.56 | 0.89 |
| Cr, mg/dL | 1.0 (0.9 to 1.2) | 1 (0.8 to 1.2) | 0.0 (-0.2 to 0.1) | 1.0 (0.8 to 1.2) | 0.9 (0.7 to 1.1) | -0.1 (-0.2 to 0.1) | 0.06 | 0.52 |
Values represent median (interquartile range). BUN - blood urea nitrogen; cmm - cubic millimeter; Cr - creatinine; CVA - cerebrovascular accident; EF - ejection fraction; Hct - hematocrit; Hgb - hemoglobin; IL - interleukin; mg/dL - milligram/deciliter; ng/dL - nanogram/deciliter; pg/dL - picogram/deciliter; Plt - platelet; Post-Op - post-operative; Pre-Op - preoperative; TNF - tumor necrosis factor; Trop-T - troponin-T; WBC - white blood cell