Table 3.
Comparison of resting cardiovascular mechanics
| Group I (n=25) | Group II (n=25) | P | |
|---|---|---|---|
| Systolic parameters | |||
| LVEF, % | 39±7 | 64±6 | <0.01 |
| Ees, mm Hg.mL–1 | 1.2±0.4 | 1.6±0.6 | <0.01 |
| V0, mL | 6.5±33 | -34±20 | <0.01 |
| Diastolic parameters | |||
| V15, mL | 156±57 | 109±23 | <0.01 |
| ß | 6.4±2.4 | 5.8±0.1 | 0.26 |
| Cvent | 0.08±0.04 | 0.09±0.03 | 0.45 |
| E/A ratio | 1.6±1.4 | 1.1±0.5 | 0.11 |
| E/e’ | 11.8±4.8 | 9.3±2.6 | 0.03 |
| Arterial parameters | |||
| Ea, mm Hg.mL–1 | 1.9±0.7 | 1.8±0.5 | 0.60 |
| Ca, mL.mm Hg–1 | 1.9±0.8 | 1.7±0.8 | 0.50 |
| SVR, dyne.s.cm–5 | 1665±664 | 1705±666 | 0.83 |
| AP, mm Hg | 7.6±4.9 | 10.2±6.9 | 0.13 |
| AIx, % | 22±11 | 26±10 | 0.18 |
| AIx@75, % | 18±12 | 21±9 | 0.29 |
| Ventriculo-arterial coupling | |||
| Ees/Ea | 1.6±0.5 | 1.1±0.3 | <0.01 |
Values are mean±standard deviation
P value was calculated using independent samples t-test
AIx - augmentation index; AIx@75 - augmentation index at 75 beats per minute; AP - augmentation pressure; ß - left ventricular stiffness constant; Ca - total arterial compliance; Cvent - left ventricular compliance; E/A - mitral Doppler early to late diastolic velocity ratio; E/e’ - early diastolic mitral Doppler to mitral annular tissue Doppler ratio; Ea - end-systolic arterial elastance; Ees - end-systolic left ventricular elastance; LVEF - left ventricular ejection fraction; SVR - systemic vascular resistance; V0 - zero intercept of the end-systolic pressure–volume relationship; V15 - volume on the diastolic pressure–volume relationship curve corresponding to 15 mm Hg