Table 4. The six prognostic genes upon whose expression the BCT algorithm was based.
| Gene group | Gene symbol | Full name | GO terms (biological process) |
|---|---|---|---|
| Proliferation | UBE2C | Ubiquitin-conjugating enzyme E2C | Cell division; mitotic cell cycle; mitotic spindle assembly checkpoint |
| TOP2A | Topoisomerase (DNA) II alpha | DNA topological change; mitotic cell cycle | |
| RRM2 | Ribonucleotide reductase M2 | G1/S transition of mitotic cell cycle; mitotic cell cycle | |
| FOXM1 | Forkhead box M1 | G2/M transition of mitotic cell cycle; mitotic cell cycle | |
| MKI67 | Marker of proliferation Ki-67 | DNA metabolic process; cell proliferation | |
| Immune response | BTN3A2 | Butyrophilin, subfamily 3, member A2 | T cell-mediated immunity; interferon-gamma secretion |
Abbreviation: GO, gene ontology.