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. 2017 Mar 28;9(9):469–476. doi: 10.4254/wjh.v9.i9.469

Table 3.

Diagnostic performance of serum alpha-fetoprotein and annexin A2 in the discrimination of patients with hepatocellular carcinoma from those with chronic liver disease

Variable Cut-off Sn (%) Sp (%) NPV (%) PPV (%) Efficacy
AFP (ng/mL) 19.8 70 96 61.5 97.2 78.7
ANXA2 (ng/mL) 18 74 88 62.9 92.5 78.7

AFP: Alpha-fetoprotein; ANXA2: Annexin A2; Sn: Sensitivity; Sp: Specificity; NPV: Negative predictive value; PPV: Positive predictive value.