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. 2017 Mar 28;9(9):477–486. doi: 10.4254/wjh.v9.i9.477

Figure 2.

Figure 2

Expression of hepatitis B virus DNA and antigens after transfection of Huh 7 cells with wild type hepatitis B virus genotype D clone (WT) and mutants with S gene mutations P120T (120T) and S143L (143L). A and B represent the extracellular expression of HBsAg and HBcrAg, respectively, by WT and S gene mutants (120T and 143L); C represents the intracellular expression of the core gene product (HBcrAg) by WT and S gene mutant clones; D: The density of the single-stranded DNA in Southern blot analysis of cell lysates of Huh7 cells transfected with WT and mutants with S gene mutations.