Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 28;7:45645. doi: 10.1038/srep45645

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(A) Whole mount preparation of the spleen and hilar structures at E16.5 shows numerous NCC on the hilum and a small number within the spleen. (B) Upper panel: 16 μm section showing tdTomato NCC entering the spleen (Sp) along the hilum (splenic artery SA, stomach St) express EdnrB (yellow in merged panels). Lower Panel: High magnification of boxed region in upper panel. (C) At E17.5, tdTomato NCC enter the spleen from the hilum and colonize the organ. (C’) High magnification view of a single splenic NCC at E17.5. (D) By P0, large numbers of NCC have colonized the spleen in an arborized pattern. Arrowheads (white) highlight individual splenic NCC. Scale bars: A 200 μm, B 50 μm, C 200 μm, C’ 20 μm, D 200 μm.