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Myelocytomatosis oncogene (MYC)-dependent Immunity. As schematically shown here, MYC plays a role in regulating a range of innate and adaptive immune cells. MYC is a key transcription factor that regulates immune cell maturation, development, proliferation and activation. MΦ- Macrophages; DC- Dendritic cells; iNKT- invariant Natural killer T cells; BCR- B cell receptor; Ab- Antibody; Ag- Antigen; M1- Classically activated macrophages; M2- alternatively activated macrophages-
