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. 2017 Mar 29;90(1):87–95.

Figure 2.

Figure 2

Activation of Cx43 hemichannels under ischemic conditions. Activation of Cx43 hemichannels (HCs) participates in the damage of cardiomyocytes, glia and renal tubule cells in ischemia. The pathways of activation have not been clearly defined, but there is evidence for all those indicated in the figure.