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Genotype frequencies of SOD2 rs4880 polymorphism in PAH cases and controls.
| rs4880 T > C | Cases, n (%) | Controls, n (%) | OR (95% CI) a | p a |
|---|---|---|---|---|
| TT | 319 (69.35%) | 426 (80.37%) | Reference | - |
| TC | 111 (24.13%) | 99 (18.68%) | 1.35 (0.79–2.81) | 0.195 |
| CC | 30 (6.52%) | 5 (0.94%) | 3.81 (1.22–5.67) | 0.013 |
| TC + CC | 141 (30.65%) | 104 (19.62%) | 2.75 (1.23–3.98) | 0.010 |
| p trend | 0.023 |
a adjusted for age and sex in additive model in logistic regression.
