Table 1.
Metabolic parameters.
| Measure | Time post-surgery | Control | HFS | Pair-fed | VSG |
|---|---|---|---|---|---|
| Total body weight (g) | 8 weeks | 29.2 ± 1.7 | 52.3 ± 4.2*** | 48.3 ± 4.9*** | 45.5 ± 7.0***;†† |
| Weight gain after surgery (g) | 8 weeks | −0.4 ± 1.0 | 7.8 ± 2.5** | 3.1 ± 2.9 | 1.5 ± 5.4†† |
| Fat mass (g) | 8 weeks | 2.7 ± 0.4 | 19.5 ± 2.9*** | 16.1 ± 3.1*** | 14.9 ± 5.0***;†† |
| Lean body mass (g) | 8 weeks | 23.6 ± 1.1 | 26.5 ± 1.4*** | 25.3 ± 1.5* | 25.8 ± 1.4** |
| eWAT weight (g) | 8 weeks | 0.45 ± 0.12 | 2.03 ± 0.64*** | 2.36 ± 0.46*** | 2.28 ± 0.91*** |
| iWAT weight (g) | 8 weeks | 0.26 ± 0.05 | 1.88 ± 0.31*** | 1.86 ± 0.45*** | 1.73 ± 0.82*** |
| Plasma insulin after 4 h fast (ng/ml) | 6 weeks | 0.38 ± 0.09 | 2.75 ± 1.75*** | 1.79 ± 0.73*** | 2.01 ± 1.16*** |
| Blood glucose after 4 h fast (mg/dl) | 6 weeks | 135 ± 18 | 190 ± 18*** | 164 ± 26 | 178 ± 35** |
| Plasma FFA in the fed state (uM) | 5 weeks | 173 ± 57 | 244 ± 63 | 243 ± 63 | 213 ± 95 |
| Plasma FFA after 16 h fast (uM) | 5 weeks | 435 ± 75 | 408 ± 94 | 356 ± 93 | 432 ± 138 |
| Delta FFA (fast minus fed) (uM) | 5 weeks | 262 ± 62 | 164 ± 106 | 113 ± 61** | 219 ± 118‡ |
End points of metabolic relevance. Values are given as mean ± std deviation. *p < 0.05, **p < 0.01, ***p < 0.001 as compared to the chow group; †p < 0.05, ††p < 0.01, ††p < 0.001 as compared to the HFD group; ‡‡p < 0.01, ‡‡‡p < 0.001 as compared to the pair-fed group.