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Table III. Down-regulated proteins, identified in group 4. Gene and protein names are truncated from the UniProtKB IDs to the first highlighted entry for each. SigP, the number of p-values for iTRAQ ratios significantly different from 1, out of a possible 12 samples. Median ITRAQ, the median unadjusted iTRAQ value across all of the samples for that protein comparing MM cell lines to a non-malignant mesothelial cell secretome.