Figure 2.
Results of the mixed models regression for the change per year in cognitive function test scores from baseline for each of the nutrients tested:
A. Comparison of the main effects of omega-3 LCPUFAs vs. no omega-3 LCPUFAs.
LCPUFAs: Long Chain Polyunsaturated Fatty Acids
TICS: Telephone Interview of Cognitive Status
Composite score. A composite score was constructed by including the score of the TICS and all the cognitive tests by converting all test results into z-scores and then averaging the z-scores. The composite score was computed to obtain an overall score for the battery of cognitive function tests, ranging from −22 to 17, with higher scores representing better function.
Telephone Interview Cognitive Status-Modified (TICS-M)3 is a version of the Mini Mental State Examination. The score for TICS ranges from 0 to 39 points. See supplementary methods for explanation for the scores of the other cognitive function tests.
Worse means a deterioration of the score for that given nutrient and better means an improved score for those randomized to omega3 fatty acids, DHA/EPA.
These analyses are adjusted for the following baseline covariates: age, gender, race, education, smoking, hypertension, congestive heart failure, and depression scale.
B: Comparison of the main effects of lutein/zeaxanthin vs. no lutein/zeaxanthin.
Lut/Zea: Lutein/Zeaxanthin
TICS: Telephone Interview of Cognitive Status
Composite score. A composite score was constructed by including the score of the TICS and all the cognitive tests by converting all test results into z-scores and then averaging the z-scores. The composite score was computed to obtain an overall score for the battery of cognitive function tests, ranging from −22 to 17, with higher scores representing better function.
Telephone Interview Cognitive Status-Modified (TICS-M)3 is a version of the Mini Mental State Examination. The score for TICS ranges from 0 to 39 points. See supplementary methods for explanation for the scores of the other cognitive function tests.
Worse means a deterioration of the score for that given nutrient and better means an improved score for those randomized to lutein/zeaxanthin.
These analyses are adjusted for the following baseline covariates: age, gender, race, education, smoking, hypertension, congestive heart failure, and depression scale.
C: Comparison of the main effects of high zinc vs. low zinc.
TICS: Telephone Interview of Cognitive Status
Composite score. A composite score was constructed by including the score of the TICS and all the cognitive tests by converting all test results into z-scores and then averaging the z-scores. The composite score was computed to obtain an overall score for the battery of cognitive function tests, ranging from −22 to 17, with higher scores representing better function.
Telephone Interview Cognitive Status-Modified (TICS-M)3 is a version of the Mini Mental State Examination. The score for TICS ranges from 0 to 39 points. See supplementary methods for explanation for the scores of the other cognitive function tests.
Worse means a deterioration of the score for that given nutrient and better means an improved score for those randomized to zinc.
These analyses are adjusted for the following baseline covariates: age, gender, race, education, smoking, hypertension, congestive heart failure, and depression scale.
D: Comparison of the main effects of beta-carotene vs. no beta-carotene.
TICS: Telephone Interview of Cognitive Status
Composite score. A composite score was constructed by including the score of the TICS and all the cognitive tests by converting all test results into z-scores and then averaging the z-scores. The composite score was computed to obtain an overall score for the battery of cognitive function tests, ranging from −22 to 17, with higher scores representing better function.
Telephone Interview Cognitive Status-Modified (TICS-M)3 is a version of the Mini Mental State Examination. The score for TICS ranges from 0 to 39 points. See supplementary methods for explanation for the scores of the other cognitive function tests.
Worse means a deterioration of the score for that given nutrient and better means an improved score for those randomized to beta-carotene.
These analyses are adjusted for the following baseline covariates: age, gender, race, education, smoking, hypertension, congestive heart failure, and depression scale.