Table 1.
Baseline Characteristics of AREDS2 Participants in at Least One Analysis by Assignment to Omega-3 Long-Chain Polyunsaturated Fatty Acids (LCPUFAs)
| No LCPUFAs (N=1526) |
LCPUFAs (N=1547) |
P-value | |
|---|---|---|---|
| Baseline Characteristic | N (%) | N (%) | |
| Age, mean (SD), y | 72.7 (7.8) | 72.7 (7.7) | 0.88 |
| Female | 858 (56.2) | 909 (58.8) | 0.16 |
| Race | |||
| White | 1485 (97.3) | 1501 (97.0) | 0.85 |
| Black | 14 (0.9) | 21 (1.4) | |
| Asian | 9 (0.6) | 9 (0.6) | |
| American Indian | 2 (0.1) | 3 (0.2) | |
| Native Hawaiian or Other Pacific Islander | 2 (0.1) | 1 (0.1) | |
| Other | 14 (0.9) | 12 (0.8) | |
| Education | |||
| High school or less | 442 (29.0) | 456 (29.5) | 0.08 |
| At least some college | 720 (47.2) | 773 (50.0) | |
| Post-graduate | 364 (23.9) | 318 (20.6) | |
| Smoking status | |||
| Never | 649 (42.5) | 664 (42.9) | 0.53 |
| Former | 769 (50.4) | 789 (51.0) | |
| Current | 108 (7.1) | 94 (6.1) | |
| Aspirin use | 740 (48.5) | 762 (49.3) | 0.67 |
| CES-D score, mean (SD) | 15.7 (6.3) | 16.1 (6.6) | 0.08 |
| Statin use | 686 (45.0) | 672 (43.4) | 0.40 |
| History of: | |||
| Hypertension | 872 (57.1) | 902 (58.3) | 0.51 |
| Congestive heart failure | 57 (3.7) | 51 (3.3) | 0.51 |
| Coronary heart disease | 154 (10.1) | 130 (8.4) | 0.11 |
| Myocardial infarction | 106 (6.9) | 84 (5.4) | 0.08 |
| Stroke | 74 (4.8) | 78 (5.0) | 0.80 |
Abbreviations: AREDS2, Age-Related Eye Disease Study 2; SD, standard deviation; CES-D, Center for Epidemiologic Studies’ Depression Scale.
P-values are from χ2 tests for categorical variables and t-test for numeric variables.