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. 2017 Mar 28;12(3):e0174089. doi: 10.1371/journal.pone.0174089

Table 2. Crude and adjusted odds-ratio (OR) of statistically significant associations of possible determinants with skin prick test (SPT) to at least one allergen or B. tropicalis or D. pteronyssinus in 481 children with specific IgE to the respective allergens.

Possible determinants Positive SPT for at least one allergen in children with specific IgE
N(%) Crude Adjusted
OR(95%CI) OR(95% CI)
No. of siblings
0–1 211 (73.3) 1 1
> = 2 105 (54.4) 0.44 [0.30–0.64] 0.54 [0.35–0.81]
*Intestinal helminth infection
No 283 (69.9) 1 1
Yes 33 (43.4) 0.44 [0.28–0.68] 0.55 [0.34–0.89]
Rodent infestation in household
No 158 (72.5) 1 1
Yes 158 (60.1) 0.57 [0.39–0.84] 0.61 [0.40–0.93]
Cat in household
No 296 (68.1) 1 1
Yes 20 (43.5) 0.36 [0.19–0.67] 0.27 [0.13–0.54]
Epstein-Barr virus
No 50(78.1) 1 1
Yes 269(63.4) 0.48 [0.26–0.91] 0.49 [0.26–0.93]
Herpes simplex virus
No 171(73.1) 1 1
Yes 151(58.8) 0.52 [0.36–0.77] 0.50 [0.34–0.74]
% of neighborhood with daily garbage collection
> = 66% 109 (71.7) 1 1
33% - 66% 39 (76.5) 1.28 [0.61–2.68] 1.67 [0.75–3.72]
0–33% 168 (60.4) 0.60 [0.39–0.92] 0.56 [0.35–0.89]
Possible determinants Positive SPT to B. tropicalis in children with specific IgE
Number of siblings
0–1 164 (62.1) 1 1
> = 2 80 (46.2) 0.52 [0.36–0.77] 0.58 [0.38–0.88]
*Intestinal helminth infections
No 217 (58.7) 1 1
Yes 27 (40.3) 0.63 [0.39–0.99] 0.80 [0.49–1.31]
Rodent infestation in household
No 126 (63.0) 1 1
Yes 118 (49.8) 0.58 [0.40–0.85] 0.58 [0.39–0.87]
Cat in household
No 231 (58.3) 1 1
Yes 13 (31.7) 0.33 [0.17–0.66] 0.27 [0.13–0.57]
Possible determinants Positive SPT to D. pteronyssinus in children with specific IgE
% of neighborhood with daily garbage collection
> = 66% 56 (66.7) 1 1
33% - 66% 24 (70.6) 0.70 [0.36–1.36] 0.75 [0.37–1.56]
0–33% 88 (56.8) 0.59 [0.39–0.91] 0.55 [0.35–0.87]
Herpes simplex virus infection
No 94 (68.6) 1 1
Yes 74(54.4) 0.56 [0.33–0.89] 0.54 [0.32–0.91]

All adjusted ORs were adjusted for a priori confounders (age, gender and parenteral asthma), and Ascaris lumbricoides and Trichuris trichiura infections.

*Ascaris lumbricoides and Trichuris trichiura infections.