Table 2. Crude and adjusted odds-ratio (OR) of statistically significant associations of possible determinants with skin prick test (SPT) to at least one allergen or B. tropicalis or D. pteronyssinus in 481 children with specific IgE to the respective allergens.
Possible determinants | Positive SPT for at least one allergen in children with specific IgE | ||
N(%) | Crude | Adjusted | |
OR(95%CI) | OR(95% CI) | ||
No. of siblings | |||
0–1 | 211 (73.3) | 1 | 1 |
> = 2 | 105 (54.4) | 0.44 [0.30–0.64] | 0.54 [0.35–0.81] |
*Intestinal helminth infection | |||
No | 283 (69.9) | 1 | 1 |
Yes | 33 (43.4) | 0.44 [0.28–0.68] | 0.55 [0.34–0.89] |
Rodent infestation in household | |||
No | 158 (72.5) | 1 | 1 |
Yes | 158 (60.1) | 0.57 [0.39–0.84] | 0.61 [0.40–0.93] |
Cat in household | |||
No | 296 (68.1) | 1 | 1 |
Yes | 20 (43.5) | 0.36 [0.19–0.67] | 0.27 [0.13–0.54] |
Epstein-Barr virus | |||
No | 50(78.1) | 1 | 1 |
Yes | 269(63.4) | 0.48 [0.26–0.91] | 0.49 [0.26–0.93] |
Herpes simplex virus | |||
No | 171(73.1) | 1 | 1 |
Yes | 151(58.8) | 0.52 [0.36–0.77] | 0.50 [0.34–0.74] |
% of neighborhood with daily garbage collection | |||
> = 66% | 109 (71.7) | 1 | 1 |
33% - 66% | 39 (76.5) | 1.28 [0.61–2.68] | 1.67 [0.75–3.72] |
0–33% | 168 (60.4) | 0.60 [0.39–0.92] | 0.56 [0.35–0.89] |
Possible determinants | Positive SPT to B. tropicalis in children with specific IgE | ||
Number of siblings | |||
0–1 | 164 (62.1) | 1 | 1 |
> = 2 | 80 (46.2) | 0.52 [0.36–0.77] | 0.58 [0.38–0.88] |
*Intestinal helminth infections | |||
No | 217 (58.7) | 1 | 1 |
Yes | 27 (40.3) | 0.63 [0.39–0.99] | 0.80 [0.49–1.31] |
Rodent infestation in household | |||
No | 126 (63.0) | 1 | 1 |
Yes | 118 (49.8) | 0.58 [0.40–0.85] | 0.58 [0.39–0.87] |
Cat in household | |||
No | 231 (58.3) | 1 | 1 |
Yes | 13 (31.7) | 0.33 [0.17–0.66] | 0.27 [0.13–0.57] |
Possible determinants | Positive SPT to D. pteronyssinus in children with specific IgE | ||
% of neighborhood with daily garbage collection | |||
> = 66% | 56 (66.7) | 1 | 1 |
33% - 66% | 24 (70.6) | 0.70 [0.36–1.36] | 0.75 [0.37–1.56] |
0–33% | 88 (56.8) | 0.59 [0.39–0.91] | 0.55 [0.35–0.87] |
Herpes simplex virus infection | |||
No | 94 (68.6) | 1 | 1 |
Yes | 74(54.4) | 0.56 [0.33–0.89] | 0.54 [0.32–0.91] |
All adjusted ORs were adjusted for a priori confounders (age, gender and parenteral asthma), and Ascaris lumbricoides and Trichuris trichiura infections.
*Ascaris lumbricoides and Trichuris trichiura infections.