Fig 2. Comparison of antibiotic resistance prevalence among study vs. local reference Escherichia coli isolates for the 10 most frequent study clonotypes.

^a For each CT (clonotype) the most prevalent (≥ 90% of isolates) sequence type (ST), as determined by multilocus sequence typing, is shown, with its subclone determined by CH typing (H) in parentheses, where applicable. For CTs represented by multiple STs (each accounting for ≤ 90% of the constituent isolates) up to four major STs and the corresponding H subclones are listed. ^b CT571 comprises ST14 (H27), ST404 (H27) and ST1193 (H64), which all belong to clonal complex of ST14. ^c For the study set and local reference set (‘Ref’), antibiotic resistance prevalence for all E. coli and for major clonotypes is given as percent of resistant isolates in relation to the total number of isolates, overall or within the clonotype; green color indicates resistance below conventional threshold (≤ 20%), red color–above it (> 20%); the resistance within study and reference sets was compared individually for each antibiotic using a two-sided Fisher’s exact test; * P < .05.