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. 2017 Mar 28;12(3):e0174412. doi: 10.1371/journal.pone.0174412

Table 1. Characteristics for women in group with and without fetal anomaly at inclusion (T1).

Women with all four assessments/visits
Fetal anomaly (n = 48) N (%) No fetal anomaly (n = 105) N (%) P-value*
Age 19–28 years 17 (35) 25 (24) 0.223
29–33 years 20 (42) 44 (42)
34–43 years 11 (23) 36 (34)
Education < junior college 23 (48) 16 (15) <0.001
≥ junior college 25 (52) 88 (85)
Missing data 0 1 (1)
Previous children No previous children 20 (42) 59 (56) 0.135
Previous children 28 (58) 46 (44)
Married or cohabiting Yes 46 (96) 105 (100) n/a
No 2 (4) 0
Gestational age at first assessment <18 weeks 11 (23) 16 (15) 0.004
18–22 weeks 33 (69) 89 (85)**
>22 –<27 weeks 4 (8) 0
Time from suspicion of fetal anomaly to examination at the referral center ≤ 2 days 36 (75) n.a.
3–4 days 5 (10)
≥ 5 days 7 (15)
Change in diagnosis/prognosis from T1 to T2 Improvement 18 (38) 0 <0.001
Stable 28 (58) 104 (99)
Worsening 2 (4) 1 (1)***
Classification of severity (see text) 1 0 n/a
2 6 (13)
3 9 (19)
4 15 (31)
5 18 (38)

* Chi-Square tests.

** In the group without fetal anomaly one case was moved to the 18–22 weeks group due to statistical purposes. This case was included in the study at week 22 + 1 day of gestation.

*** One anomaly in the comparison group detected at T 3 (a cyst in one thigh).