Table 2. Responses and toxicities to chemoradiotherapy of head and neck squamous cell carcinoma patients.
| Variable | Ideal or mild | Non-ideal, moderate or severe | ||
|---|---|---|---|---|
| Type of response or grade of toxicity | N (%) | Type of response or grade of toxicity | N (%) | |
| Response rate | CR+PR | 68 (93.2) | SD | 5 (6.8) |
| CR | 15 (20.5) | PR+SD | 58 (79.5) | |
| Gastrointestinal toxicities | ||||
| Nausea | G0+G1 | 37 (42.0) | G2+G3 | 51 (58.0) |
| Vomiting | G0+G1 | 59 (67.0) | G2+G3+G4 | 29 (33.0) |
| Hematologic toxicities | ||||
| Anemia | G0+G1 | 37 (44.0) | G2+G3+G4 | 47 (56.0) |
| Leukopenia | G0+G1 | 47 (56.0) | G2+G3+G4 | 37 (44.0) |
| Neutropenia | G0+G1+G2 | 67 (79.8) | G3+G4 | 17 (20.2) |
| Lymphopenia | G0+G1+G2 | 42 (50.0) | G3+G4 | 42 (50.0) |
| Thrombocytopenia | G0 | 54 (64.3) | G1+G2+G3+G4 | 30 (35.7) |
| Nephrotoxicity | G0+G1 | 36 (52.2) | G2+G3+G4+G5 | 33 (47.8) |
| Ototoxicity | G0+G1 | 36 (51.4) | G2+G3+G4 | 34 (48.6) |
(N) number of patients; (CR) complete response; (PR) partial response; (SD) stable disease; (G) grade of toxicity. The total number of patients differed from the total quoted in the study (n= 90), because it was not possible to obtain consistent information about response rate, nausea and vomiting, hematologic exams, glomerular filtration rate or audiometry test after chemoradiotherapy in some cases.