Table 1. Basic characteristics of patients from the two cohorts.
| Variables | Discovery set (N, %)(n=642) | Replication set (N, %)(n=330) | χ2 | Pa |
|---|---|---|---|---|
| Age (years) | ||||
| < 58 | 333 (51.9) | 171 (51.8) | 0.001 | 0.988 |
| ≥ 58 | 309 (48.1) | 159 (48.2) | ||
| Gender | ||||
| Male | 456 (71.0) | 234 (70.9) | 0.001 | 0.969 |
| Female | 186 (29.0) | 96 (29.1) | ||
| Smoking history | ||||
| Non-smokers | 260 (40.5) | 144 (43.6) | 0.884 | 0.347 |
| Smokers | 382 (59.5) | 186 (56.4) | ||
| ECOG PS | ||||
| 0-1 | 593 (92.4) | 297 (90.0) | 1.582 | 0.209 |
| 2 | 49 (7.6) | 33 (10.0) | ||
| Chemotherapy | ||||
| NP/NC | 236 (36.8) | 115 (34.8) | 1.126 | 0.771 |
| GP/GC | 174 (27.1) | 95 (28.8) | ||
| TP/TC | 192 (29.9) | 95 (28.8) | ||
| DP/DC | 40 (6.2) | 25 (7.6) | ||
| TNM stage | ||||
| III | 262 (40.8) | 119 (36.1) | 2.063 | 0.151 |
| IV | 380 (59.2) | 211 (63.9) | ||
| Histological type | ||||
| Adeno | 398 (62.0) | 213 (64.5) | 2.057 | 0.358 |
| SQC | 147 (22.9) | 66 (20.0) | ||
| Others | 97 (15.1) | 51 (15.5) |
Adeno adenocarcinoma, SQC squamous cell carcinoma, a p-values derived from χ2 test.