Table 3. Multivariate Cox's regression analysis of prognostic factors for overall survival in Discovery set.

Variables	HR (95% CI)	P
Age (≥ 58 vs. < 58)	1.21 (1.01-1.45)	0.053
TNM stage (IV vs. III)	1.29 (1.07-1.55)	0.008
Histological type		0.014
Adeno	Ref.
SQC	1.26 (1.00-1.58)	0.049
Others	1.40 (1.08-1.82)	0.011
rs10900598
dominant	0.78 (0.64-0.97)	0.023
rs4245739
dominant	0.67 (0.50-0.90)	0.007

Adeno adenocarcinoma, SQC squamous cell carcinoma. All the variables yielding P-values< 0.1 in the univariate analysis were used for multivariate Cox's regression.