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. 2017 Jan 13;8(10):16356–16366. doi: 10.18632/oncotarget.14633

Figure 2. Downregulation of YAP by SJAMP contributes to inhibition pancreatic cancer cells growth.

Figure 2

(A) With the prolong of effect time of 8 mg/ml SJAMP on the pancreatic cancer cells, the expression level of YAP, TEAD1, survivin mRNA decreased significantly, and the expression level of Caspase-9, MST1 mRNA increased significantly. (B) The same tendency was observed when effected by SJAMP in different dose. (C) and (D) After affected by SJAMP, the protein level of YAP decreased and the protein level of pYAP increased obviously. *p < 0.05, **p < 0.01.