Table 1. The relationship between YAP expression in pancreatic cancer tissue strength and clinical pathological factors.
| Negative | Weakly positive | Moderately positive | Strongly positive | χ2 | P | |
|---|---|---|---|---|---|---|
| Gender | 0.643 | 0.577 | ||||
| Male | 2 | 3 | 5 | 10 | ||
| Female | 1 | 2 | 10 | 12 | ||
| Age | 0.787 | 0.565 | ||||
| > 60 | 1 | 4 | 8 | 13 | ||
| < 60 | 2 | 1 | 7 | 9 | ||
| Smoking | 1.452 | 0.541 | ||||
| Yes | 3 | 4 | 9 | 15 | ||
| No | 0 | 1 | 6 | 7 | ||
| Drinking | 1.896 | 0.224 | ||||
| Yes | 1 | 3 | 11 | 16 | ||
| No | 2 | 2 | 4 | 6 | ||
| BMI | 0.000 | 1.000 | ||||
| BMI > 27 | 2 | 4 | 9 | 15 | ||
| BMI < 27 | 1 | 1 | 6 | 7 | ||
| Abnormal glucose tolerance | 1.773 | 0.542 | ||||
| Yes | 3 | 3 | 9 | 14 | ||
| No | 0 | 2 | 6 | 8 | ||
| Diabetes | 0.952 | 0.555 | ||||
| Yes | 1 | 2 | 8 | 16 | ||
| No | 2 | 3 | 7 | 6 | ||
| Chronic pancreatitis | 0.643 | 0.577 | ||||
| Yes | 2 | 2 | 6 | 10 | ||
| No | 1 | 3 | 9 | 12 | ||
| Differentiation | 5.294 | 0.048* | ||||
| Poorly | 0 | 1 | 11 | 16 | ||
| Medium and high | 3 | 4 | 4 | 6 | ||
| T stages | 2.143 | 0.543 | ||||
| T1 | 2 | 1 | 3 | 9 | ||
| T2 | 1 | 2 | 6 | 6 | ||
| T3 | 0 | 2 | 5 | 6 | ||
| T4 | 0 | 0 | 1 | 1 | ||
| N stages | 0.592 | 1.000 | ||||
| N0 | 3 | 3 | 13 | 19 | ||
| N1 | 0 | 2 | 2 | 3 | ||
| Clinical stages | 0.153 | 0.926 | ||||
| I | 2 | 3 | 11 | 12 | ||
| II | 1 | 2 | 4 | 8 | ||
| III | 0 | 0 | 0 | 2 |
*Statistically significant
Elevated YAP activity/expression strongly correlated with tumor histological differentiation in pancreatic cancer tissue (χ2 = 5.294, p = 0.048).