Table 1. The relationship between YAP expression in pancreatic cancer tissue strength and clinical pathological factors.
Negative | Weakly positive | Moderately positive | Strongly positive | χ2 | P | |
---|---|---|---|---|---|---|
Gender | 0.643 | 0.577 | ||||
Male | 2 | 3 | 5 | 10 | ||
Female | 1 | 2 | 10 | 12 | ||
Age | 0.787 | 0.565 | ||||
> 60 | 1 | 4 | 8 | 13 | ||
< 60 | 2 | 1 | 7 | 9 | ||
Smoking | 1.452 | 0.541 | ||||
Yes | 3 | 4 | 9 | 15 | ||
No | 0 | 1 | 6 | 7 | ||
Drinking | 1.896 | 0.224 | ||||
Yes | 1 | 3 | 11 | 16 | ||
No | 2 | 2 | 4 | 6 | ||
BMI | 0.000 | 1.000 | ||||
BMI > 27 | 2 | 4 | 9 | 15 | ||
BMI < 27 | 1 | 1 | 6 | 7 | ||
Abnormal glucose tolerance | 1.773 | 0.542 | ||||
Yes | 3 | 3 | 9 | 14 | ||
No | 0 | 2 | 6 | 8 | ||
Diabetes | 0.952 | 0.555 | ||||
Yes | 1 | 2 | 8 | 16 | ||
No | 2 | 3 | 7 | 6 | ||
Chronic pancreatitis | 0.643 | 0.577 | ||||
Yes | 2 | 2 | 6 | 10 | ||
No | 1 | 3 | 9 | 12 | ||
Differentiation | 5.294 | 0.048* | ||||
Poorly | 0 | 1 | 11 | 16 | ||
Medium and high | 3 | 4 | 4 | 6 | ||
T stages | 2.143 | 0.543 | ||||
T1 | 2 | 1 | 3 | 9 | ||
T2 | 1 | 2 | 6 | 6 | ||
T3 | 0 | 2 | 5 | 6 | ||
T4 | 0 | 0 | 1 | 1 | ||
N stages | 0.592 | 1.000 | ||||
N0 | 3 | 3 | 13 | 19 | ||
N1 | 0 | 2 | 2 | 3 | ||
Clinical stages | 0.153 | 0.926 | ||||
I | 2 | 3 | 11 | 12 | ||
II | 1 | 2 | 4 | 8 | ||
III | 0 | 0 | 0 | 2 |
*Statistically significant
Elevated YAP activity/expression strongly correlated with tumor histological differentiation in pancreatic cancer tissue (χ2 = 5.294, p = 0.048).