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. 2017 Jan 27;8(10):16473–16487. doi: 10.18632/oncotarget.14869

Figure 2. Loss of MTSS1 leads to a more invasive and migratory, but not more proliferative phenotype in PDAC.

Figure 2

(A) Scratch assays were performed in both serum-containing and serum-free conditions with PANC-1 (–) and PANC-1 siMTSS1 cells. (B) Representative scratch assay images of PANC-1 (–) and PANC-1 siMTSS1 cells in either the presence or absence of serum. Images were taken at 10X magnification. (C) PANC-1 (–) and PANC-1 siMTSS1 cells were plated for a transwell migration assay in the presence of Matrigel, stained with hematoxylin, and counted after 48 hours of incubation. (D) PANC-1 (–) and PANC-1 siMTSS1 cells were plated and harvested at various timepoints to determine any changes in proliferative abilities. *p-value < 0.05, **p-value < 0.001.