Figure 3. Fli-1 transactivating compounds induce megakaryocytic differentiation in erythroleukemia cell lines.
Treatment of the erythroleukemic cell lines HEL A. and CB7 B. with A236 and TPA increases the percentage and level of CD41 expression, 48 hours post- treatment. C. These compounds only weakly induce CD41 expression in K562 cells. Compound concentration, 5μM.