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. 2017 Feb 9;8(10):16951–16963. doi: 10.18632/oncotarget.15208

Figure 4. ELF3 expression is associated with epithelial phenotypes of ovarian cancer cells.

Figure 4

Correlation studies were performed to study the association between the expression levels for ELF3 and EMT markers. Using expression profiles from 108 microdissected ovarian tumor samples, ELF3 expression was found to be positively correlated with the expression levels for the epithelial markers (A) β-catenin, (B) E-cadherin, (C) and β-catenin–interacting protein 1 and negatively correlated with the expression level for (D) the EMT-driving transcription factor Snail. (E) Immunostaining of ovarian tumor tissue sections from the same ovarian cancer patient for ELF3 and E-cadherin expression suggested that they were positively correlated at the protein level (R = 0.456, p = 0.008). S, stroma, T, tumor. Bar = 50 μm.