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. 2017 Feb 3;8(10):17092–17104. doi: 10.18632/oncotarget.15060

Table 5. Characteristics for encephalocele and congenital hydrocephalus of infants and their mother (isolated versus non-isolated).

Characteristics Encephalocele Congenital hydrocephalus
Isolated Non-isolated P value Isolated Non-isolated P value
No. of cases 301 103 2039 969
Time of diagnosis (%) 0.09 0.94
 During pregnancy 270 (89.7) 98 (95.2) 1926 (94.5) 916 (94.5)
 Within 7 days after delivery 31 (10.3) 5 (4.8) 113 (5.5) 53 (5.5)
Prognosis status (%) 0.08 0.90
 Live birth 20 (6.6) 2 (1.9) 91 (4.5) 49 (5.1)
 Stillbirth 50 (16.6) 13 (12.6) 270 (13.2) 129 (13.3)
 Dead within 28 days 10 (3.3) 1 (1.0) 65 (3.2) 32 (3.3)
 Inducing labor 221 (73.5) 87 (84.5) 1613 (79.1) 759 (78.3)
Mother
No. of pregnancy (%) 0.02 0.27
 0 4 (1.3) 0 (0) 4 (0.2) 5 (0.5)
 1 142 (47.2) 63 (61.2) 1051 (51.5) 509 (52.5)
 ≥2 155 (51.5) 40 (38.8) 984 (48.3) 455 (47.0)
No. of live births (%) 0.03 <0.001
 0 117 (38.9) 54 (52.4) 464 (22.8) 374 (38.6)
 1 142 (47.1) 41 (39.8) 1246 (61.1) 446 (46.0)
 ≥2 42 (14.0) 8 (7.8) 329 (16.1) 149 (15.4)
Age, years (%) 0.18 0.09
 <20 10 (3.3) 3 (2.9) 51 (2.5) 32 (3.3)
 20-25 75 (24.9) 25 (24.3) 603 (29.5) 318 (32.8)
 25-30 106 (35.2) 49 (47.6) 725 (35.6) 309 (31.9)
 30-35 70 (23.3) 18 (17.5) 392 (19.2) 170 (17.5)
 ≥35 40 (13.3) 8 (7.7) 268 (13.2) 140 (14.5)
Race (%) 0.43 0.48
 Han 263 (87.4) 93 (90.3) 1774 (87.0) 834 (86.1)
 Others 38 (12.6) 10 (9.7) 265 (13.0) 135 (13.9)
Income level (%) 0.80 0.006
 < 600 yuan 22 (7.3) 8 (7.8) 164 (8.0) 72 (7.4)
 600-1200 yuan 47 (15.6) 12 (11.7) 280 (13.7) 177 (18.3)
 1200-2400 yuan 86 (28.6) 30 (29.1) 569 (27.9) 279 (28.8)
 ≥ 2400 yuan 146 (48.5) 53 (51.4) 1026 (50.4) 441 (45.5)
Education level (%) 0.41 0.21
 Elementary school or less 24 (8.0) 5 (4.9) 137 (6.7) 86 (8.9)
 Middle school 184 (61.1) 58 (56.3) 1288 (63.2) 594 (61.3)
 High school 44 (14.6) 20 (19.4) 357 (17.5) 170 (17.5)
 College or above 49 (16.3) 20 (19.4) 257 (12.6) 119 (12.3)
Infant
Gestational age, week (%) 0.03 <0.001
 <28 228 (75.8) 87 (84.5) 840 (41.2) 576 (59.4)
 28-37 33 (11.0) 12 (11.7) 867 (42.5) 265 (27.4)
 ≥37 40 (13.2) 4 (3.8) 332 (16.3) 128 (13.2)
Birth weight, gram (%) 0.014 <0.001
 <2500 257 (85.4) 99 (96.1) 1537 (75.4) 793 (81.8)
 2500-4000 42 (14.0) 4 (3.9) 468 (23.0) 171 (17.7)
 ≥4000 2 (0.6) 0 (0) 34 (1.6) 5 (0.5)
Sex (%) 0.23 <0.001
 Male 128 (42.5) 53 (51.5) 1088 (53.4) 449 (46.3)
 Female 152 (50.5) 42 (40.8) 922 (45.2) 492 (50.8)
 Unknown 21 (7.0) 8 (7.7) 29 (1.4) 28 (2.9)
Multiple births (%) 0.14 0.37
 Yes 4 (1.3) 4 (3.9) 60 (2.9) 23 (2.4)
 No 297 (98.7) 99 (96.1) 1979 (97.1) 946 (97.6)

† Income level was presented as per person per year.