Fig 4. Compensatory changes in CYP protein expression in Cyp3a-null mice.
Western blots of male and female Cyp3a-null mice show significant changes in CYP expression relative to their WT counterparts. Results are expressed as relative mean of the WT compared to CAR-null mice of the same sex. Statistical differences were determined by Student’s t-tests (n = 3) with * (p < 0.05) ** (p < 0.01) *** (p < 0.001) indicating significant differences.