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. 2017 Mar 23;10:1809–1819. doi: 10.2147/OTT.S122803

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© 2017 Wang et al. This work is published and licensed by Dove Medical Press Limited

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(A) Comparisons of mRNA expression of Nrf2 signaling pathway in HSC-4 and HSC-4-RR cell lines before and after transfection. (B) Comparisons of protein expression of Nrf2 by Western blotting in HSC-4 and HSC-4-RR cell lines before and after transfection. (C) Comparisons of protein expression of Nrf2 signaling pathway in HSC-4 and HSC-4-RR cell lines before and after transfection. *P<0.05 compared with the HSC-4-NC group; ^#P<0.05 compared with the HSC-4-RR-NC group; ^&P<0.05 compared with the HSC-4-Nrf2 siRNA group.

Abbreviations: GST, glutathione S-transferase; HO1, heme oxygenase-1; HSC-4, HSC-4 human squamous cell carcinoma cell line; NC, negative control; NQO1, NADPH quinine oxidoreductase 1; Nrf2, nuclear factor erythroid 2-related factor 2; RR, radiation resistance.